Why Doctors Insist on Single Embryo Transfers
I.Multiple Pregnancy Crisis: Why does the medical community “talk about double”? The global advancement of assisted reproductive technology (ART) has led to a significant increase in clinical pregnancy rates, but the ensuing multiple pregnancies have become the most serious complication. Data show that the preterm birth rate of twin pregnancies is as high as 60%, and the rate of triple pregnancies is even closer to 100% – not only threatening the safety of mothers and babies, but also posing a heavy medical burden. Hypertension during pregnancy: the incidence rate of twin pregnancies reaches 40%, which is four times higher than that of single pregnancies.Post-partum hemorrhage: uterine over-distension leads to weak contractions and a 3-fold increase in the risk of bleeding >1000ml.Long-term health effects: multiple pregnancies raise the probability of gestational diabetes remaining as type 2 diabetes by 30%. Very low birth weight (VLBW): 50% of twins with birth weight <2500g have a 25% increased risk of neurodevelopmental delay.Congenital malformations: Twin fetuses have twice the rate of single fetus malformations, with a 4.6% incidence of heart defects.Case warning: 32-year-old Emma was pregnant with twin babies from a double embryo transfer. Cervical insufficiency occurred at 26 weeks’ gestation, and ultimately neither of the babies survived. II.The Scientific Advantages of Single Embryo Transfer (SET): Data-Driven Selection Developmental potential assessment: only 40% of fertilized eggs can develop to blastocyst stage (day 5-6), eliminating chromosomally abnormal embryos naturally.Morphologic grading: 65% of Grade AA blastocysts (good quality of both inner cell mass and trophectoderm) are deposited, which is significantly higher than the 45% of Day 3 embryos. Comparison of clinical data norm single blastocyst transfer Double cleavage stage embryo transfer Clinical pregnancy rate 62% 58% live birth rate 55% 48% Multiple pregnancy rate 1.2% 35% Preterm birth rate (<37 weeks) 7% 60% RESEARCH SUPPORT: The New…
