Surrogacy techniques

Higher probability of having a son with IVF? Global data on 1 million in vitro babies turns perceptions on their head

2025-03-06

    ‘Harvard Reproductive Centre leaks data: 8.3% more likely to have a boy with IVF than a natural pregnancy? But 90% of clinics will never tell you this secret’   Cognitively upsetting data  ▶️ Statistics of 1 million IVF babies worldwide show:  ▸ Natural pregnancy male to female ratio 105:100  ▸ IVF male to female ratio 107:100  (Data source: Frontiers in Human Reproductive Medicine 2023)   ⚠️ WARNING: When you find a clinic with a ‘boy birth rate’ of over 53%, they may be manipulating gender with these 3 techniques – a grey area even in countries where it’s legal.   The secrets of the gender scales  The ‘invisible pushers’ of embryo labs:  X sperm are weaker?Y sperm swim faster? The truth is – blastocyst culture technique itself screens out 23% of female embryos (due to differences in metabolic rates of X chromosome embryos)  Sex code of frozen embryos:  Male embryo resuscitation survival rate is 17% higher than female under vitrification freezing technique (Kyrgyzstan Reproductive Centre 2024 report data)  Precise manipulation of transfer timing:  Male embryo implantation rate increased by 9.6% when transferred 12 hours before the endometrial tolerance period (The Hidden Function of ERA Testing)  Global Testimonials  ▫️ Los Angeles: Emily’s 3 unsuccessful transfers of female embryos led to the birth of a male baby after switching to the Metabolomics Preferred protocol.  ▫️ London: Couple carrying haemophilia gene blocked Y-chromosome defects through PGD technology and finally got a healthy baby girl.  ▫️ The Royal Family of Dubai: In order to balance the gender of their children, they chose to freeze cleavage stage embryos for 7 consecutive times (a programme with a higher proportion of female embryos).  Red Line Alert: These Behaviours Can Get You Blackballed from Global Reproductive Clinics  Asking for ‘custom gender’ under non-medical indications (89% of European and American clinics will terminate services immediately)  Attempting to separate X/Y sperm by sperm centrifugation (proven risk of serious genetic damage)  Falsely…

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Failed 3 times in New York? Central Asian clinic goes so far as to use NASA-grade embryo algorithms to blow up live birth rates to 87 percent

2025-03-06

    Failed 3 times in New York? Central Asian clinic goes so far as to use NASA-grade embryo algorithms to blow up live birth rates to 87 per cent  ‘The secret California fertility centres have been hiding for 15 years: fly embryos from patients with repeated implantation failures to Kyrgyzstan and the live birth rate soars to 87% – now even Harvard professors are secretly flying patients over.’    ‘Getting a $98,000 bill for a 4th failed implantation only to have the New York clinic tell you “it could be an immune problem”-they should have done ERA testing the first time around!’  ‘Your embryos are experiencing ‘uterine escapades’: 57% of recurrent failure cases actually require only 0.3 days of adjustment to the transfer window!’  Kyrgyzstan’s ‘Implantation Revolution’ programme:  ‘NASA algorithms + combatant embryologists: calculating optimal timing of implantation with a missile trajectory model with an error of ±2 hours’  (Data Bomb: in 2023 we enabled 193 patients with 3+ failures to carry their babies, 87% of which were reversed with aneuploid embryos)  ‘Endometrial Tolerance Assay (ERA) on Thursday, AI report on Friday, precision transfer the following Monday – a speed that puts US clinics to shame’  ‘1/5th of the price to enjoy the upgraded PGT-A: not only screening chromosomes, but also analysing embryo mitochondrial energy value – those below 90% are directly eliminated’  Perception-bending comparison:  ‘LA clinic charges 3,500 to do ERA vs 890 for a full implant window programme in Kyrgyzstan – not a technology gap, but a conscience gap.’  Real life case blitz:  Case 1: Jessica in Texas had 4 failed transplants and was found to have 300% excess NK cell activity. We used a fat emulsion + heparin regimen and had a successful double pregnancy on the 5th time.  Case 2: David of London had 47% sperm DNA fragmentation, we initiated testicular puncture + IMSI sperm superselection and ended up…

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Higher age donor egg IVF success rate vs Senior Self Egg IVF Success Rate, What exactly is the best choice for fertility at an advanced age?

2025-03-06

In the field of assisted reproduction, more and more senior women with the dream of having children embark on the road of IVF. However, when faced with the two choices of donor egg IVF and self-egg IVF, many people are torn, after all, they have different success rates and each has its own characteristics. Today, let’s have an in-depth chat about the success rate of senior donor egg IVF and senior self-egg IVF, and analyse how to make a suitable choice for senior childbearing, hoping to give some reference and help to friends who are confused.   First, the success rate of high-age self-egg in vitro test tube situation  1. The decline in egg quality affects the success rate  With age, women’s ovarian function will gradually decline, especially at an advanced age (usually refers to 35 years old and above, more obvious after 40 years old), the number of eggs in the sharp decrease at the same time, the quality of the decline is also obvious. The probability of chromosomal abnormalities in the eggs increases dramatically, which results in the formation of embryos with poorer developmental potential after fertilisation, and a lower proportion of good quality embryos, which in turn affects the success of the subsequent transfer of embryos and the likelihood of their continued healthy development.  According to statistics, the success rate of IVF for women aged 35 – 40 is around 30% – 40%; at the age of 40 – 45, the success rate is only 10% – 20%; above the age of 45, the success rate is even lower, often less than 10%, and it is even difficult to get pregnant after several attempts, which is enough to show that the age has a great impact on the success rate of IVF.  For example, Xiaolin, who started IVF at the age of…

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Why Doctors Insist on Single Embryo Transfers

2025-03-05

I.Multiple Pregnancy Crisis: Why does the medical community “talk about double”? The global advancement of assisted reproductive technology (ART) has led to a significant increase in clinical pregnancy rates, but the ensuing multiple pregnancies have become the most serious complication. Data show that the preterm birth rate of twin pregnancies is as high as 60%, and the rate of triple pregnancies is even closer to 100% – not only threatening the safety of mothers and babies, but also posing a heavy medical burden. Hypertension during pregnancy: the incidence rate of twin pregnancies reaches 40%, which is four times higher than that of single pregnancies.Post-partum hemorrhage: uterine over-distension leads to weak contractions and a 3-fold increase in the risk of bleeding >1000ml.Long-term health effects: multiple pregnancies raise the probability of gestational diabetes remaining as type 2 diabetes by 30%. Very low birth weight (VLBW): 50% of twins with birth weight <2500g have a 25% increased risk of neurodevelopmental delay.Congenital malformations: Twin fetuses have twice the rate of single fetus malformations, with a 4.6% incidence of heart defects.Case warning: 32-year-old Emma was pregnant with twin babies from a double embryo transfer. Cervical insufficiency occurred at 26 weeks’ gestation, and ultimately neither of the babies survived. II.The Scientific Advantages of Single Embryo Transfer (SET): Data-Driven Selection Developmental potential assessment: only 40% of fertilized eggs can develop to blastocyst stage (day 5-6), eliminating chromosomally abnormal embryos naturally.Morphologic grading: 65% of Grade AA blastocysts (good quality of both inner cell mass and trophectoderm) are deposited, which is significantly higher than the 45% of Day 3 embryos. Comparison of clinical data norm single blastocyst transfer Double cleavage stage embryo transfer Clinical pregnancy rate 62% 58% live birth rate 55% 48% Multiple pregnancy rate 1.2% 35% Preterm birth rate (<37 weeks) 7% 60% RESEARCH SUPPORT: The New…

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