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Complete Clinical Path and Technical Analysis of Artificial Insemination

Artificial Insemination (AI) is an assisted reproductive technology in which processed semen is injected directly into the female reproductive tract (mainly intrauterine insemination) through non-coital means. The core principle is to increase the probability of sperm meeting the egg by optimizing the path and timing of sperm delivery. Depending on the source of sperm, it is categorized into artificial insemination by husband (AIH), which is suitable for men with mild to moderate oligozoospermia or sexual dysfunction, and artificial insemination by donor (AID), which is for couples with azoospermia or a high risk of genetic disorders. Compared to In Vitro Fertilization (IVF), the advantages of AI are that it is easy to perform (on average, it takes 15 minutes), inexpensive (the…

What criteria must the lining of the uterus and follicles meet in order to conceive?

　　　　“What kind of lining and follicles are necessary for pregnancy?　　Generally speaking, a woman can get pregnant only if her follicles are 18mm-25mm in size and her uterine lining is 8mm-12mm thick.　　If the follicle is smaller than 18mm, the ability of fertilization is poor, and it is difficult to get pregnant after discharge; if it is larger than 25mm, the follicle is difficult to be discharged, and it is easy to be luteinized, and it is not possible to get pregnant normally.　　The endometrium is also the same, too thin or too thick is not conducive to the fertilization of the egg, and even if it does, it is prone to miscarriage, fetal arrest, and ultimately lead to infertility.　　“What is the relationship…

Is it true that 3G IVF affects the quality of blastocysts?

Blastocyst is the ultimate stage of in vitro embryo culture and the stage at which human embryos are implanted into the mother. Blastocysts are more mature than cleavage stage embryos and are better suited to grow in the uterine environment.　　In case of third generation IVF, when the blastocysts are ready, the doctor will need to biopsy the embryos in order to select good quality genetic embryos, which will increase the patient’s chances of conception, improve the live birth rate, reduce the risk of multiple pregnancies, and save the cost and time of IVF. 　　Many people will have this question: the embryos are already very fragile, and if some of them are taken out for testing, will it cause any harm…

2025 Efficient solutions for recurrent miscarriages due to follicular dysplasia

Introduction: The Underestimated Fertility Threat When Emily had her third miscarriage, her doctor told her, “Your problem is not repeated miscarriages, but difficulty getting pregnant at all.” Data shows that 86.17% of infertile women suffer from follicular dysplasia, while 73.2% of spontaneous miscarriage patients suffer from the same problem. The quality of follicles not only determines the chances of conception, but also affects the health of embryos – this invisible killer is quietly destroying the fertility hopes of countless families. I. Clinical signs of follicular dysplasia 1.1 Gold standard of normal follicles Mature follicles should have the following characteristics: Morphology: full round or oval shape, 18-22mm in diameter, thin and clear inner wall.Functionality: accompanied by clear, pulpy cervical mucus and…

Does IVF Ovulation Promotion Harm the Body?

　　　　Does multiple ovulation induction for IVF cause great harm to the body? In the process of IVF treatment, in order to get more eggs to increase the chance of pregnancy, except for the natural cycle, generally women have to take medication to promote ovulation. However, for many women whose ovarian function is not very good, the number of ovulated follicles is small, and the chance of success of IVF is greatly reduced, so it is inevitable that they will go through the experience of repeated ovulation. So, is it harmful to the body to do IVF ovulation several times? 　　1. Will the use of ovulation induction drugs lead to premature ovarian failure?　　The number of eggs in each woman’s body is…

Winter Fetal Arrest Crisis: How Pre-Thrombotic State Becomes the “Invisible Killer” of Embryos?

Winter Fetal Arrest Crisis: How Pre-Thrombotic State Becomes the “Invisible Killer” of Embryos? I. Behind the scene of 60% of fetal arrests: the neglected prethrombotic state In the field of reproductive medicine, pre-thrombotic state (PTS) is becoming the number one risk factor for recurrent pregnancy loss. Recent multinational studies have shown that 62.8% of fetal terminations and biochemical pregnancies are directly related to maternal PTS, with the prevalence being 40% higher in winter than in other seasons. This tendency of hypercoagulability is like a time bomb that silently cuts off the embryo’s lifeline. Placental microthrombosis: maternal blood hypercoagulation leads to thrombosis of spiral arteries, blocking the oxygen and nutrient supply to the embryo.Trophoblastic dysfunction: Hyperfibrinogenemia (>4g/L) inhibits chorionic angiogenesis and…

IVF Clinic Tells You PGD Ends Family Hereditary Diseases

Introduction: The Hidden Truth of Medicine and Hope for New Life When Emily suffered her fifth miscarriage, her American doctor told her, “Your BRCA1 mutation gene makes the embryo survival rate less than 15%.” But the turnaround came in an email from Kyrgyzstan – where 85% of PGD cycle clients get mutation-free embryos in one go, compared to the European average of 2.3 cycles. This is not only a technological gap, but also a revolution in medical ethics. I. The scientific revolution of PGD technology: from theory to clinical practice 1.1 Precise sniping for gene editing PGD (preimplantation genetic diagnosis) can screen for single-base mutations to chromosomal structural abnormalities by extracting blastocyst trophoblast cells and utilizing whole genome amplification and…

High-quality eggs mostly have these hints under ultrasound!

Introduction: Egg quality – the biological cornerstone of fertility success Global reproductive medicine data show that egg quality is the core factor affecting conception rate and embryo health. A study covering 100,000 IVF cycles found that the clinical pregnancy rate for high quality eggs (65%) was 3 times higher than for low quality eggs. Ultrasound technology, as the “golden eye” for non-invasive assessment of follicular development, can reveal the potential of eggs in advance. In this article, we will combine the latest international research to decode the ultrasound characteristics of high-quality follicles and scientific cultivation strategies. I. Follicle quality under ultrasound: the double standard of morphology and function maldevelopment Diameter range（mm） Ultrasonic Characterization clinical significance pre-sinusoidal follicle 0.2-2 Echo-free zone…

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